EFFECTS OF DISOPYRAMIDE ON THE MAXIMUM RATE OF RISE OF ACTION POTENTIAL (Vmax) IN GUINEA-PIG PAPILLARY MUSCLES
نویسندگان
چکیده
منابع مشابه
Combined effects of rate membrane potential, and drugs on maximum rate of rise (Vmax) of action potential upstroke of guinea pig papillary muscle.
We studied the effect of increasing the rate of stimulation on the maximum rate of rise of the action potential upstroke (Vmax) in guinea pig papillary muscles at various resting membrane potentials and after the addition of quinidine and lidocaine to the perfusate. Increasing rate caused a decrease in Vmax due to interaction of three factors: (1) a metabolic factor, presumably resetting of the...
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ژورنال
عنوان ژورنال: Japanese Journal of Pharmacology
سال: 1982
ISSN: 0021-5198
DOI: 10.1016/s0021-5198(19)52720-2